APPLICATIONS CATEGORY - ILE Complete Film Coating Systems

APPLICATIONS CATEGORY - ILE Complete Film Coating Systems
Product Type	Product Name & Specification		Main Materials	Solubility	Solvent System	Concentration of Coating Solvent (Pigmented & white/Clear)	Operation Temperature	Recommended Weight Gain (Pigmented & white / Clear)	Products Characteristics and Range of Application
EASPRAY™ Immediate Release	Regular Film Coatings	GAI	HPMC Plasticizer Titanium Dioxide	Independent on pH value. Film dissolve completely within 100 seconds in water and stimulated gastric fluids	30%-70% Ethanol	8%-10%/ 6%-7%	40±2℃	2%-6%/ 1%-3%	The tensile strength of film membrane is high, which can protect the tablet core from abrasion, can cover the defects of bad tablet core. Good appearance properties and glossy film membrane. Under recommended conditions, the coating suspension with moderate viscosity about 100 mpa.s is easy to operate; Be suitable for coating with various kinds of coating equipments. Good integrated properties, be suitable for coating various dosage forms.
	Regular Film Coatings	GAIV	HPMC Plasticizer Titanium Dioxide		Pure Water	12%-14%/ 6%-8%	40±2℃	2%-6%/ 1%-3%
	Separated Film Coatings	GOI	HPMC Polysaccharide polymer Plasticizer Colorant Titanium Dioxide	Independent on pH value. Film dissolve completely within 100 seconds in water and stimulated gastric fluids	Pure Water	12% - 14%/ 6% - 8%	40±2℃	2%-6%/ 1%-3%	Operates on aqueous system. Have the properties of EASPRAY regular coatings, Permeability to gas is lower than that of regular type. Be suitable for the drug contains volatile substance, such as the drug contains borneol and/or oil substance, etc.
	Separated Film Coatings	GPI	HPMC Plasticizer Titanium Dioxide		Pure Water 30% - 70% Ethanol	10% -12%with water 8% - 10% with Ethanol	40±2℃	1%-3%/ 1%-3%	Be white film coating agent with good masking effects, be suitable for coating the isolated layer of herbal medicine. Low permeability to vapor and oxygen, which can protect the medicine from corrading of vapor and the drug effective ingredients seeping out that lead to color changes.
	Efficient Film Coatings	GMI	Polyvinyl Alcohol (PVA) Plasticizer Colorant Titanium Dioxide	Independent on pH value. Film dissolve completely within 120 seconds in water and stimulated gastric fluids	Pure Water	16%-18%/ 6%-8%	42±2℃	2%-6%/ 1%-3%	Operates on aqueous system. Under recommended solid content, the coating suspension with moderate viscosity about 50 mpa.s is easy to atomizing and operating. Comparing with the regular coatings, the operation time is reduced. The film membrane have separated functions, can prevent oxygen from entering, which increase the stability of tablet core. Good adhesion, decreases the possibility of bridging and chipping. Glossy appearance.
	Lozenge Film Coatings	GKI	Polyvinyl Alcohol (PVA) / HPMC Plasticizer Colorant Titanium Dioxide	Film dissolves rapidly within 40 seconds under saliva environment ( pH6.4~7.0)	Pure Water 30% - 70% Ethanol	16%-20%/ 6%-8% 8%-10%/ 6%-8%	45±2℃ 42±2℃	1%-3%/ 1%-3% 1%-3%/ 1%-3%	Wider solvent and solid content application range; Under recommended solid content, with viscosity about 50-120mpa.s, it is suitable for various kinds of coating equipments. The film adhesion is high, especially be suitable for the troche contains saccharide and surface modifiers. Can add flavoring agent to obtain the same flavor of the drug.
	Moisture Barrier Film Coatings	GAIII	HPMC Plasticizer Colorant Titanium Dioxide	Independent on pH value. Film dissolves completely within 100 seconds in water and stimulated gastric fluids	80% - 95% Ethanol	8%-10%/ 6%-8%	40±2℃	2%-6%/ 1%-3%	The properties of GAIII are similar with the common properties of EASPRAY regular coating. Be suitable for water-sensitive tablet cores, especially for the isolated layer of dispersible tablets, fast-disintegrating oral tablets and alkalescence enteric dosage forms. When application, using 80% ethanol as solvent can obtain better appearance.
EASCOL™ Enteric Release	EOQL55		HPMCP Plasticizer Colorant Titanium Dioxide	Dependent on pH value. Dissolve ≥pH5.5	80% Ethanol	8%-10%	30±2℃	10%-12%	Film membrane dissolve at the front of small intestine, with fast drug release and enhanced bioavailability. The film membrane has good mechanical intensity which provide better protection to the tablet core. With 10%-12% weight gain, the film membrane have good ability to withstand gastric acid for 2 hours; When pH ≥5.5, the membrane begin to dissolve. Take 80% ethanol as solvent, which yields high coating efficiency, low energy consumption, and low requirement on dryness efficiency of coating equipment.
	EOBS68		Polyacrylic Resin Plasticizer Colorant Titanium Dioxide	Dependent on pH value. Dissolve ≥ pH6.8	75% - 80% Ethanol	8%-10%	35±2℃	5%-6%	Good anti-acid property, to withstand gastric acid effectively for 2 hours with 4%-6% weight gain; the membrane dissolve when pH ≥6.8. Low viscosity, be prone to atomization, glossy film membrane. Can operate on various solvent systems; Moderate material cost; Be suitable for coating various kinds of enteric dosage forms. Take 80% ethanol as solvent, which yields high coating efficiency, low energy consumption, and low requirement on dryness efficiency of coating equipment.
	EABL55		Polyacrylic Resin Plasticizer Colorant Titanium Dioxide	Dependent on pH value. Dissolve ≥ pH5.5	Pure Water	18%-20%	35±2℃	7%-10%	Operate on aqueous system. Can withstand gastric acid effectively for 2 hours with 7%-10% weight gain; the membrane dissolve when pH≥5.5. The well coating suspension can be obtained within 30 minutes, when application stir is required at any moment. With high solid content, and higher manufacturing efficiency.